Trade name of the drug ľ Actovegin
1 film-coated tablet contains:
Core: Active ingredient: Blood Components: deproteined hemo-derivative blood of calves - 200 mg, magnesium stearate, povidone (K 90), talc, cellulose.
Sheath: acacia gum, mountain wax glycol, hypromellose phthalate, diethyl phthalate, quinoline yellow dye aluminum lacquer macrogol (6000), Povidone (K 30), sucrose, talc, titanium dioxide.
Description: brilliant greenish yellow round coated tablets.
Pharmacotherapeutic group: tissue regeneration stimulator.
PharmacodynamicsAntihypoxants. AKTOVEGIN hemoderivat is that obtained by dialysis and ultrafiltration (tested compound with a molecular weight less than 5000 daltons). Positively affects the transport and utilization of glucose stimulated oxygen consumption (which leads to stabilization of the plasma membranes of cells during ischemia and reduce the formation of lactate) having thus anti-hypoxic action, which begins to appear at the latest 30 minutes after oral administration and reaches a peak in the middle after 3 hours (2-6 hours).Actovegin increases the concentration of adenosine triphosphate, adenosine, phosphocreatine, and amino acids - glutamate, aspartate, and gamma-aminobutyric acid.
Using methods impossible pharmacokinetic study Actovegin pharmacokinetic drug because it consists only of physiological components that normally present in the body.
So far not found to decrease hemo-derivate pharmacological effect in patients with altered pharmacokinetics (eg, hepatic or renal failure, metabolic changes associated with old age, and especially in newborns metabolism).
Hypersensitivity to the drug AKTOVEGIN« or similar drugs.
Heart failure II and III level, pulmonary edema, oliguria, anuria, hyperhydration; pregnancy, lactation.
Application of pregnancy and lactation is allowed.
Dosage and administration:
Inside, 1-2 tablets 3 times a day, without chewing, the food, squeezed small amounts of liquid. The duration of treatment should be between 4 and 6 weeks.
Allergic reactions (eg, urticaria, edema, drug fever). In such cases, treatment should be discontinued Actovegin. If necessary, a standard therapy of allergic reactions (antihistamines and / or corticosteroids).
Interaction with other drugs
It is currently unknown.
3 years. Do not use beyond the expiration date.
The temperature is not above 25 ░ C in a dark place. Keep out of reach of children!
Conditions of supply of pharmacies
Tablets 200 mg film-coated.
On 50 tablets in dark glass bottles (type III of, Evr.farm.) With screw neck and screw cap, which provides control of the first opening. 1 bottle with instruction on use is placed in a cardboard box. In a pack of transparent protective paste stickers round shape with topographical inscriptions and control of the first opening.